主题词：Single-cell and spatial transcriptomics; Genetic Associations and Epidemiology; Genomics and Chromatin Dynamics; Cancer Genomics and Diagnostics; CRISPR and Genetic Engineering; Epigenetics and DNA Methylation; RNA Research and Splicing; RNA modifications and cancer; Genomics and Rare Diseases; Chromosomal and Genetic Variations; RNA and protein synthesis mechanisms; Bioinformatics and Genomic Networks; Genetic Mapping and Diversity in Plants and Animals; Genomics and Phylogenetic Studies; Cancer-related molecular mechanisms research; Genomic variations and chromosomal abnormalities; Gene expression and cancer classification; Cell Image Analysis Techniques; T-cell and B-cell Immunology; Genetic and phenotypic traits in livestock; Gene Regulatory Network Analysis; Genetics and Neurodevelopmental Disorders; Molecular Biology Techniques and Applications; Ethics in Clinical Research; Immune Cell Function and Interaction