主题词：Receptor Mechanisms and Signaling; Synthesis and biological activity; Synthesis and Biological Evaluation; Chemical Synthesis and Analysis; Computational Drug Discovery Methods; HIV/AIDS drug development and treatment; Synthesis and Characterization of Heterocyclic Compounds; Cancer therapeutics and mechanisms; Click Chemistry and Applications; Biochemical and Molecular Research; Peptidase Inhibition and Analysis; Synthesis and Reactions of Organic Compounds; Neuropeptides and Animal Physiology; Pharmacological Receptor Mechanisms and Effects; Neuroscience and Neuropharmacology Research; Phenothiazines and Benzothiazines Synthesis and Activities; Protein Degradation and Inhibitors; Bioactive Compounds and Antitumor Agents; Estrogen and related hormone effects; Chemical synthesis and alkaloids; Quinazolinone synthesis and applications; Carbohydrate Chemistry and Synthesis; Adenosine and Purinergic Signaling; Drug Transport and Resistance Mechanisms; Analytical Chemistry and Chromatography