主题词：Carcinogens and Genotoxicity Assessment; DNA and Nucleic Acid Chemistry; Pharmacogenetics and Drug Metabolism; DNA Repair Mechanisms; Computational Drug Discovery Methods; Chemistry and Chemical Engineering; Genomics, phytochemicals, and oxidative stress; History and advancements in chemistry; Free Radicals and Antioxidants; Effects and risks of endocrine disrupting chemicals; Synthesis and Biological Evaluation; Pesticide Exposure and Toxicity; Toxic Organic Pollutants Impact; Drug Transport and Resistance Mechanisms; Metabolomics and Mass Spectrometry Studies; Drug-Induced Hepatotoxicity and Protection; Sulfur Compounds in Biology; Analytical Chemistry and Chromatography; Nitric Oxide and Endothelin Effects; Air Quality and Health Impacts; Glutathione Transferases and Polymorphisms; Bioactive Compounds and Antitumor Agents; Heavy Metal Exposure and Toxicity; Cancer therapeutics and mechanisms; Eicosanoids and Hypertension Pharmacology