主题词：Mast cells and histamine; Asthma and respiratory diseases; Immune Response and Inflammation; Inflammatory mediators and NSAID effects; Receptor Mechanisms and Signaling; Polyamine Metabolism and Applications; Neuropeptides and Animal Physiology; Coagulation, Bradykinin, Polyphosphates, and Angioedema; Cell Adhesion Molecules Research; Amino Acid Enzymes and Metabolism; Rheumatoid Arthritis Research and Therapies; Osteoarthritis Treatment and Mechanisms; Neutrophil, Myeloperoxidase and Oxidative Mechanisms; Nitric Oxide and Endothelin Effects; Immune cells in cancer; Food Allergy and Anaphylaxis Research; Allergic Rhinitis and Sensitization; Inflammasome and immune disorders; Eicosanoids and Hypertension Pharmacology; Cytokine Signaling Pathways and Interactions; Immune Cell Function and Interaction; Neuroendocrine regulation and behavior; NF-κB Signaling Pathways; Adenosine and Purinergic Signaling; Pain Mechanisms and Treatments