主题词：Genetics, Aging, and Longevity in Model Organisms; Epigenetics and DNA Methylation; Telomeres, Telomerase, and Senescence; Alzheimer's disease research and treatments; Neuroinflammation and Neurodegeneration Mechanisms; Dementia and Cognitive Impairment Research; Single-cell and spatial transcriptomics; Health, Environment, Cognitive Aging; Immune cells in cancer; Circadian rhythm and melatonin; Frailty in Older Adults; Diet and metabolism studies; Tryptophan and brain disorders; Adipose Tissue and Metabolism; Mitochondrial Function and Pathology; Autophagy in Disease and Therapy; Dietary Effects on Health; Gut microbiota and health; Health disparities and outcomes; Birth, Development, and Health; Aging and Gerontology Research; Reproductive Biology and Fertility; Muscle Physiology and Disorders; RNA Research and Splicing; Neurogenesis and neuroplasticity mechanisms