主题词：Cancer, Hypoxia, and Metabolism; Cancer-related Molecular Pathways; Monoclonal and Polyclonal Antibodies Research; Cancer Genomics and Diagnostics; HER2/EGFR in Cancer Research; Lung Cancer Treatments and Mutations; Cancer Research and Treatments; PI3K/AKT/mTOR signaling in cancer; Ubiquitin and proteasome pathways; Protein Degradation and Inhibitors; RNA modifications and cancer; Cancer Treatment and Pharmacology; Cancer therapeutics and mechanisms; Microtubule and mitosis dynamics; DNA Repair Mechanisms; Advanced Breast Cancer Therapies; Cancer Mechanisms and Therapy; Epigenetics and DNA Methylation; Peptidase Inhibition and Analysis; Cell death mechanisms and regulation; Histone Deacetylase Inhibitors Research; Colorectal Cancer Treatments and Studies; Cancer Cells and Metastasis; CAR-T cell therapy research; PARP inhibition in cancer therapy