主题词：BRCA gene mutations in cancer; Genomics and Rare Diseases; Cancer-related molecular mechanisms research; RNA modifications and cancer; MicroRNA in disease regulation; Folate and B Vitamins Research; Epigenetics and DNA Methylation; Genetic Associations and Epidemiology; Ethics in Clinical Research; Prenatal Screening and Diagnostics; Adipokines, Inflammation, and Metabolic Diseases; Genetic factors in colorectal cancer; Genomic variations and chromosomal abnormalities; Hearing, Cochlea, Tinnitus, Genetics; Pharmacogenetics and Drug Metabolism; Cancer Genomics and Diagnostics; Circular RNAs in diseases; Glutathione Transferases and Polymorphisms; Hemoglobinopathies and Related Disorders; Immune Response and Inflammation; Protease and Inhibitor Mechanisms; DNA Repair Mechanisms; RNA Research and Splicing; Molecular Biology Techniques and Applications; Blood Coagulation and Thrombosis Mechanisms